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Drug ReportsLinzagolix choline
Linzagolix choline
Yselty (linzagolix choline) is a small molecule pharmaceutical. Linzagolix choline was first approved as Yselty on 2022-06-14. It is used to treat endometriosis in the USA. It has been approved in Europe to treat leiomyoma.
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Therapeutic Area
MeSH
neoplasmsD009369
urogenital diseasesD000091642
Trade Name
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ATC Codes
H: Systemic hormonal preparations, excl. sex hormones and insulins
H01: Pituitary and hypothalamic hormones and analogues
H01C: Hypothalamic hormones
H01CC: Anti-gonadotropin-releasing hormones
H01CC04: Linzagolix
HCPCS
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Drug
General
Drug common nameLinzagolix choline
INN
Description
Linzagolix, sold under the brand name Yselty, is a medication used in the treatment of uterine fibroids. Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) developed by Kissei Pharmaceutical and ObsEva.
Classification
Small molecule
Drug classgonadotropin releasing hormone (GnRH) receptor antagonists (nonpeptide)
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Structure (InChI/SMILES or Protein Sequence)
COc1cc(F)c(-n2c(=O)[nH]c3csc(C(=O)[O-])c3c2=O)cc1OCc1c(OC)ccc(F)c1F.C[N+](C)(C)CCO
Identifiers
PDB
CAS-ID935283-04-8
RxCUI
ChEMBL IDCHEMBL4298171
ChEBI ID
PubChem CID16656889
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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